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Can microscopic living organisms change the effects of drugs?

Can microscopic living organisms change the effects of drugs?



In our gut, there are trillions of microscopic organisms, including at least a thousand different species of organisms, containing three million different genetic compounds. The effects of most medications are not the same in different people. The form and severity of side effects from the same drug also vary from person to person

 When the medicine is absorbed by the intestines after taking it, the medicine also comes in contact with the microscopic organisms living there.  These microscopic organisms can cause significant changes in the effects of drugs.

Some important investigations about microorganisms living in the human body

 According to a recent study published in the popular scientific journal "Nature", scientists have discovered that microscopic organisms can change the chemical form of drugs before they are absorbed.

The study found evidence that microscopic organisms have greatly increased the effects of drugs or even converted them into toxic compounds.

There are many types of microscopic organisms found in the stomach, even though the total genetic mix of microscopic organisms is a hundred times more than all the genes in our human body. Recent research examined 20,000 pairs of medicinal and microscopic organisms and examined more than 6,000 resulting chemical compounds.

 As a result of the effects of microscopic animal drugs, some drugs became effective, such as sulfa silazane, while others became ineffective, such as digoxin. Surprisingly, many drugs turned into toxic compounds, such as so iodine, broaden, irinotecan. It is generally believed that most drugs are absorbed through the small intestine and do not reach microscopic organisms that usually reside in the large intestine.

In fact, medicines are not fully absorbed by the small intestine, and some of them usually reach the large intestine and thus come into contact with microscopic organisms.  Recent research has also shown that the presence of certain chemical forms in chemical compounds of drugs may predict that microscopic organisms in the stomach may be affected by these drugs.

 This information can not only predict the possible effects of the drug on microscopic organisms but also prevent potentially negative changes in the effects of the drug by deliberately altering the types of microscopic organisms living in the human intestine.

 The species of microscopic organisms that live in the large intestine in the human body largely depends on our diet and healthy lifestyle.

Benefits of  Microorganisms living in human intestines

 These organisms, which live in the intestines of a healthy human being, use the undigested substances from our food as food and in turn, protect our intestines from the invasion of pathogens and produce vitamins and other beneficial ingredients for the human body.  But if the balance of these microscopic organisms is disturbed, they can produce very harmful compounds for health, which can lead not only to intestinal inflammation but also to many other chronic diseases.

Fecal transplantation

Fecal transplantation has long been practiced in the Western world to restore this disturbed balance of microscopic organisms. In this process, the waste excreted from the body of a healthy person is inserted into the colon of a sick person through an endoscopy tube. But this treatment has not been so popular in the Eastern world

 You may have seen the news on the BBC last year in which healthy people were asked to donate their waste.  Even today, in hospitals in England, patients with CDF diarrhea who cannot be cured with antibiotics are treated with fecal transplants.

 Microscopic organisms useful for human health are also bred in the breed laboratory and used in combination with food.

What are probiotics?

 These organisms are called probiotics.  Yogurt and its by-products are a common type of commonly used probiotic, containing millions of useful microscopic organisms.  In the same way, our diet also contains certain fibers and components that our body cannot digest and they become the food of these microscopic organisms in the large intestine.

What is Prebiotics?

 These indigestible nutrients are called prebiotics.  Regular use of these ingredients in the diet helps in the reproduction of health-friendly microscopic organisms that prevent the germs that spread the disease from settling in the intestines.  Thus prebiotics and probiotics have the potential to cause mutations in the species of microscopic organisms living in the human intestine.

 Therefore, it is possible that in the future, to improve the efficacy of individual medicines and to reduce their side effects, prescriptions for certain types of pre and probiotics may be prescribed.


Listen to the sound of your stomach, the secrets of many chronic diseases are hidden in the microscopic organisms in our intestines. Eat a balanced diet and lead a healthy lifestyle.

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  1. You have write an amazing article which is very helpful for me. You have done a proper research and you have took all the point in your article. I has cleared my all questions. Thanks for your article.

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